Understanding and preventing the impact of endocrine disruptors in sensitive populations
One of the first research projects to study endocrine disruptor chemicals' effects on the hypothalamus-pituitary axis
IN A NUTSHELL
Towards elucidating the health impacts of endocrine disrupting chemicals
Exposure to multiple Endocrine Disrupting Chemicals (EDCs) interferes with the function of the endocrine system, especially during developmental stages of life.
HYPIEND is one of the first projects to study EDCs effects on the hypothalamus-pituitary axis using a multidisciplinary approach, including preclinical models and two European-wide clinical studies.
The findings will be used to delineate interventional strategies for minimizing EDC exposure and consequences on the neuroendocrine system in pregnant and breastfeeding women and perinatal and pre-pubertal children.
PROJECT PHASES
A holistic approach to evaluate the effect of EDCs on the hypothalamus - pituitary axis
ALIGNED WITH USERS NEEDS
Committed to protect citizens from hazardous chemicals
According to a report from the Endocrine Society, since 2009 numerous international scientific and health organizations have raised concerns and took a public stance about the risks that EDCs pose for public health, and many have called for stronger regulations. Scientific community concerns led to several actions by the European Commission to improve its regulatory regime.
Adopted in 2018, the Comprehensive European Union Framework on Endocrine Disruptors defines the EU strategic approach on endocrine disruptors for the years to come.
In 2020, the European Union acknowledged the need for attention to EDCs and called for several specific actions, including a ban on several of these chemicals in consumer products in the Commission’s Chemicals Strategy for Sustainability.
In 2022, the EU Commission proposed new hazard classes under its chemicals regulation, including endocrine disruption, to better protect people and the environment from hazardous chemicals.
Under these regulatory frameworks and scientific concerns, HYPIEND aims at contributing to develop new endocrine disruptor screening methods and map out new public health strategies and policies to minimise the exposure of the most vulnerable populations.
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NEWS & EVENTS
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Project news
HYPIEND partner from Eurecat holds a talk about EDCs impacts on epigenetic programming at the XXXIII SEÑ Congress
The HYPIEND project was introduced as one of the ongoing European research projects on understanding and minimizing EDCs effects.
HYPIEND project consortium meets in Warsaw
Partners from the HYPIEND’s consortium gather for discussing project advances and next steps
Eurecat partners present HYPIEND Project at the ENKORE Cluster kick-off meeting
Partners from HYPIEND’s coordinator Eurecat Technology Centre presented the project at the ENKORE cluster kick-off meeting
HYPIEND partner from SCIENSANO present project’s interventional studies at Belgian PARERE meeting
HYPIEND partner Maryse Ledent (Sciensano) presented the project’s interventional studies at a meeting from the Belgian PARERE – EURL ECVAM Network
Partner from CMKP presents HYPIEND project at the conference “Lifestyle Medicine for Longevity” 2024
HYPIEND partner Alicja Baska, MD (CMKP) provided an overview of endocrine disrupting chemicals and strategies to limit exposure to them
Two project partners highlighted HYPIEND project at the Spanish Pediatric Endocrinology Conference 2024
HYPIEND partners Carmen Freire (UGR), and Paula Ventura (IGTP) gave two different talks about the impact of EDCs
HYPIEND partners participate in the first ENKORE workshop on chemical mixtures and mixed exposure to EDC
The first thematic workshop of the ENKORE Cluster provided an overview of the chemical mixtures selected by the five projects
Partners from KU Leuven present the HYPIEND use of organoid models in an international symposium
HYPIEND partners from KU Leuven have presented the project’s use of organoid models at the “3D Organ modelling in Health and Disease 2024” international symposium
European consortium to study how to reduce the impact of endocrine disruptors on pregnancy and pre-puberty
HYPIEND project is studying the impact of endocrine disruptors on the hormonal system during pregnancy, the first 18 months of a baby’s life and during pre-puberty
HYPIEND project kicks-off!
The HYPIEND project has kicked off on January 2024 in Barcelona with the objective of understanding and preventing the impact of Endocrine Disrupting Chemicals (EDC).
Upcoming events
July 3-5
XXV Congress of the Spanish Association of Toxicology (AETOX)
Presentation "Computational modelling for the study of endocrine disruption: The HYPIEND project” by ProtoQSAR partners.
Brussels, Belgium
MEET THE TEAM
HYPIEND project consortium
HYPIEND is a collaborative consortium coordinated by Eurecat that involves the collaboration of research institutions and companies, collectively working towards a holistic understanding of EDC adverse health effects during critical development stages.
This Horizon Europe project brings together epidemiologists, exposure scientists, toxicologists, endocrinologists, health case practitioners, phycologists and risk assessors to bridge science-policy gaps.
List of partners
