Understanding and preventing the impact of endocrine disruptors in sensitive populations
One of the first research projects to study endocrine disruptor chemicals' effects on the hypothalamus-pituitary axis
HYPIEND IN A NUTSHELL
Towards elucidating the health impacts of endocrine disrupting chemicals
Exposure to multiple Endocrine Disrupting Chemicals (EDCs) interferes with the function of the endocrine system, especially during developmental stages of life.
HYPIEND is one of the first projects to study EDCs effects on the hypothalamus-pituitary axis using a multidisciplinary approach, including preclinical models and two European-wide clinical studies.
The findings will be used to delineate interventional strategies for minimizing EDC exposure and consequences on the neuroendocrine system in pregnant and breastfeeding women and perinatal and pre-pubertal children.
PROJECT PHASES
A holistic approach to evaluate the effect of EDCs on the hypothalamus - pituitary axis
ALIGNED WITH USERS NEEDS
Committed to protect citizens from hazardous chemicals
According to a report from the Endocrine Society, since 2009 numerous international scientific and health organizations have raised concerns and took a public stance about the risks that EDCs pose for public health, and many have called for stronger regulations. Scientific community concerns led to several actions by the European Commission to improve its regulatory regime.
Adopted in 2018, the Comprehensive European Union Framework on Endocrine Disruptors defines the EU strategic approach on endocrine disruptors for the years to come.
In 2020, the European Union acknowledged the need for attention to EDCs and called for several specific actions, including a ban on several of these chemicals in consumer products in the Commission’s Chemicals Strategy for Sustainability.
In 2022, the EU Commission proposed new hazard classes under its chemicals regulation, including endocrine disruption, to better protect people and the environment from hazardous chemicals.
Under these regulatory frameworks and scientific concerns, HYPIEND aims at contributing to develop new endocrine disruptor screening methods and map out new public health strategies and policies to minimise the exposure of the most vulnerable populations.
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NEWS & EVENTS
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Project news
HYPIEND presents two posters at the 48th FSEEP Congress in Barcelona
IGTP has presented new findings from the HYPIEND project on children’s health, endocrine disruptors and school-based intervention research.
HYPIEND research presented at the SEGHNP Congress
HYPIEND partners delivered two presentations at the SEGHNP conference held in Salamanca, Spain during 14-15 of May.
First encounter with endocrine disruptors: the placenta as a guardian
Researchers at King’s College London explore how endocrine disruptors can cross the placenta and affect trophoblast cells, fetal development and pregnancy health.
HYPIEND research presented at Obstetrics and Gynaecology Conference in Granada
HYPIEND project was presented during the “Jornadas de Actualización en Obstetricia, Ginecología y Reproducción”, a professional training event in Granada
HYPIEND perinatal intervention study presented at BASO World Obesity Week Conference 2026
HYPIEND project was showcased at the BASO World Obesity Week Conference 2026 – Re Thinking Obesity, held on 6 March 2026 in Leuven, Belgium.
Swimming in chemicals: What zebrafish can teach us about our health
Researchers at Radboud University study, within the European HYPIEND project, how endocrine-disrupting chemicals affect hormone regulation and behaviour of individual zebrafish larvae.
Endocrine disruptors: science and innovation to prevent their harmful effects on human health
Endocrine disruptors represent a global public health challenge that requires responses grounded in scientific research and technological innovation.
A European study to reduce children’s exposure to Endocrine Disruptors that alter the hormonal system
Over a period of more than two years, schools in Belgium and Spain will participate in an initiative involving over 700 children.
ENKORE Workshop – Advancing Adverse Outcome Pathways Frameworks for Endocrine Disruption Research
First ENKORE workshop bringing together experts, researchers, and enthusiasts to explore the use of the Adverse Outcome Pathway (AOP) framework in understanding and assessing the impacts of endocrine-disrupting chemicals.
HYPIEND prepubertal study resented at the Barcelonès Nord and Maresme Paediatric Conference
Dr. Paula Ventura, researcher the Germans Trias i Pujol Research Institute (IGTP), delivered a keynote lecture entitled “Endocrine Disruptors in Paediatrics.”
MEET THE TEAM
HYPIEND project consortium
HYPIEND is a collaborative consortium coordinated by Eurecat that involves the collaboration of research institutions and companies, collectively working towards a holistic understanding of EDC adverse health effects during critical development stages.
This Horizon Europe project brings together epidemiologists, exposure scientists, toxicologists, endocrinologists, health case practitioners, phycologists and risk assessors to bridge science-policy gaps.
List of partners
