The HYPIEND project was presented during two different talks at the 2024 Spanish Society of Pediatric Endocrinology (SEEP) Conference that took place in Las Palmas de Gran Canaria (Spain) in May 8-10th. Project partners Carmen Freire, from University of Granada (UGR), and Paula Ventura, from Germans Trias i Pujol Research Institute (IGTP), gave two different talks about the impact of endocrine disrupting chemicals (EDCs). Both highlighted HYPIEND project as one of the ongoing European studies working to understand and prevent the effects of EDCs.
On May 8th Paula Ventura presented a poster on the association between exposure to bisphenol A and other synthetic phenols and risk of earlier puberty in girls. These are results of a multicentric case-control study conducted by Carmen Freire, Paula Ventura and researchers from 10 different Spanish institutions. The poster was awarded as the best poster communication of the 2024 SEEP Conference.
On May 9th, Carmen Freire presented her research work about the effects of pesticides and other EDCs on pubertal development, concluding exposure to EDCs with estrogenic and/or antiandrogenic effects during pregnancy and childhood could contribute to alterations in pubertal development, and nutritional status is a factor that may modify these associations.
Within the framework of the HYPIEND project, IGTP is in charge of an intervention studies to modulate EDC exposure in sensitive populations (1000 days of early life and pre-puberty children) by assessing the effectiveness of multicomponent strategies, the performance of biomarkers and the effectiveness of HYPIEND interventions in preventing harmful health effects linked to hypothalamus pituitary disruption. UGR will also participate in the intervention study in the first 1000 days by recruiting pregnant women, carrying out the follow-up and analyzing EDCs in breast milk samples.
The SEEP is a scientific society created in 1977 that aims to promote and stimulate the development of Pediatric and Adolescent Endocrinology. Apart from covering the role of EDCs in precocious puberty, the latest annual congress included a scientific programme covering the latest developments in paediatric endocrinology, such as GHLA or the great novelty of a therapeutic alternative for patients affected by achondroplasia, the latest advances in diabetes or pathologies such as congenital adrenal hyperplasia, or the pathophysiological bases of central hypogonadism.
