HYPIEND’s use of New Approach Methodologies (NAMs) for studying the effects of Endocrine Disrupting Chemicals (EDCs) was presented at the 13th World Congress on Alternatives and Animal Use in the Life Sciences that took place between August 31st – September 4th, 2025, in Rio de Janiero, Brasil.
ProtoQSAR CSO, Eva Serrano Candelas, showcased a poster titled “New Approach Methodologies (NAMs) for the understanding the impact of endocrine disruptors in the framework of the HYPIEND project”.
The study presents how the Horizon Europe HYPIEND project combines different NAMs together with animal and interventional studies to understand the effects of EDCs co-exposure on the function of the hypothalamus-pituitary axis and minimise the exposure and the consequences of EDCs on the neuroendocrine system during the perinatal and pre-pubertal stages. By integrating these methodologies, HYPIEND will provide a comprehensive and mechanistic understanding of EDCs-induced disruptions in neuroendocrine function.
The World Congress on Alternatives and Animal Use in the Life Sciences is a significant international event that focuses on advancing the field of alternatives to animal testing in research and education. The congress provides a platform for scientists, researchers, policymakers, and other stakeholders to exchange knowledge, share best practices, and discuss the latest developments in the field. These events play a crucial role in shaping the future direction of research and policy in this area, ultimately contributing to the promotion of more humane and scientifically sound approaches to advancing the life sciences.
